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Two-photon microscope upgrade reaches 75 nm resolution, a fivefold gain

A team at Texas A&M University has pushed two-photon microscopy to a lateral resolution of about 75 nanometres, around five times finer than the conventional version of the technique. The approach, named 2PE-ISM-SOFI, adds two established methods to a standard two-photon instrument. It was reported in the Journal of…

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